Cures Out of Chaos

Cures Out of Chaos

Author: Daniel K. Podolsky

Publisher: CRC Press

ISBN: 0367447894

Category:

Page: 430

View: 785

This volume describes important medical discoveries, from the introduction of the first antibiotic to the present, where serendipity, intuition, coincidence, or laboratory accident played an important role in bringing a discovery to light. Although chance is the principal determinant, the book emphasizes other factors, such as economic and political exigencies and being in the right place at the right time.
Medical

Cures out of Chaos

Cures out of Chaos

Author: Daniel K. Podolsky

Publisher: CRC Press

ISBN: 9057025558

Category: Medical

Page: 456

View: 639

This volume describes important medical discoveries, from the introduction of the first antibiotic to the present, where serendipity, intuition, coincidence, or laboratory accident played an important role in bringing a discovery to light. Although chance is the principal determinant, the book emphasizes other factors, such as economic and political exigencies and being in the right place at the right time.
Medical

Cures Out of Chaos

Cures Out of Chaos

Author: M. Lawrence Podolsky

Publisher: Taylor & Francis

ISBN: 9057025566

Category: Medical

Page: 430

View: 412

Shows how serendipity, intuition, or laboratory accidents have played important roles in major scientific discoveries.
Business & Economics

Pharma

Pharma

Author: Gerald Posner

Publisher: Simon and Schuster

ISBN: 9781501152030

Category: Business & Economics

Page: 816

View: 690

Award-winning journalist and New York Times bestselling author Gerald Posner reveals the heroes and villains of the trillion-dollar-a-year pharmaceutical industry and delivers “a withering and encyclopedic indictment of a drug industry that often seems to prioritize profits over patients (The New York Times Book Review). Pharmaceutical breakthroughs such as anti­biotics and vaccines rank among some of the greatest advancements in human history. Yet exorbitant prices for life-saving drugs, safety recalls affecting tens of millions of Americans, and soaring rates of addiction and overdose on pre­scription opioids have caused many to lose faith in drug companies. Now, Americans are demanding a national reckoning with a monolithic industry. “Gerald’s dogged reporting, sets Pharma apart from all books on this subject” (The Washington Standard) as we are introduced to brilliant scientists, incorruptible government regulators, and brave whistleblowers facing off against company exec­utives often blinded by greed. A business that profits from treating ills can create far deadlier problems than it cures. Addictive products are part of the industry’s DNA, from the days when corner drugstores sold morphine, heroin, and cocaine, to the past two decades of dangerously overprescribed opioids. Pharma also uncovers the real story of the Sacklers, the family that became one of America’s wealthiest from the success of OxyContin, their blockbuster narcotic painkiller at the center of the opioid crisis. Relying on thousands of pages of government and corporate archives, dozens of hours of interviews with insiders, and previously classified FBI files, Posner exposes the secrets of the Sacklers’ rise to power—revelations that have long been buried under a byzantine web of interlocking companies with ever-changing names and hidden owners. The unexpected twists and turns of the Sackler family saga are told against the startling chronicle of a powerful industry that sits at the intersection of public health and profits. “Explosively, even addictively, readable” (Booklist, starred review), Pharma reveals how and why American drug com­panies have put earnings ahead of patients.
Medical

Cancer and the Search for Selective Biochemical Inhibitors, Second Edition

Cancer and the Search for Selective Biochemical Inhibitors, Second Edition

Author: E.J. Hoffman

Publisher: CRC Press

ISBN: 1420045962

Category: Medical

Page: 480

View: 380

The world of medicine has become splintered into two factions, that of orthodoxy and its counterpart, alternative or complementary medicine. A problem with alternative medicine is, of course, that of anecdote and hearsay. The solution: the disclosure, in an unassailable fashion, of the underlying biochemical principles for alternative cancer therapies. Cancer and the Search for Selective Biochemical Inhibitors, Second Edition delineates the underlying biochemical principles for alternative cancer therapies. Completely revised and updated, this edition includes coverage of the link between concepts and practices of alternative and conventional medicine. The author examines anticancer plant substances and other alternatives such as Vitamin C, essiac tea, shark cartilage, and cat’s claw. The text also addresses the problem of determining selective and non-toxic enzyme inhibitors for cancer cell metabolic pathways. While an increased number of allopathic professionals are in tune with alternative therapies, the integration of the two factions is far from the norm. Keeping the same format that made its predecessor a benchmark text, this book compares complementary, alternative, and integrative treatments with chemotherapy and other more traditional treatments.
Medical

Superbugs

Superbugs

Author: Matt McCarthy

Publisher: Penguin

ISBN: 9780735217522

Category: Medical

Page: 304

View: 802

International Bestseller "An amazing, informative book that changes our perspective on medicine, microbes and our future." --Siddhartha Mukherjee, MD, New York Times bestselling author of The Emperor of All Maladies A New York Times bestselling author shares this exhilarating story of cutting-edge science and the race against the clock to find new treatments in the fight against the antibiotic-resistant bacteria known as superbugs. Physician, researcher, and ethics professor Matt McCarthy is on the front lines of a groundbreaking clinical trial testing a new antibiotic to fight lethal superbugs, bacteria that have built up resistance to the life-saving drugs in our rapidly dwindling arsenal. This trial serves as the backdrop for the compulsively readable Superbugs, and the results will impact nothing less than the future of humanity. Dr. McCarthy explores the history of bacteria and antibiotics, from Alexander Fleming's discovery of penicillin, to obscure sources of innovative new medicines (often found in soil samples), to the cutting-edge DNA manipulation known as CRISPR, bringing to light how we arrived at this juncture of both incredible breakthrough and extreme vulnerability. We also meet the patients whose lives are hanging in the balance, from Remy, a teenager with a dangerous and rare infection, to Donny, a retired New York City firefighter with a compromised immune system, and many more. The proverbial ticking clock will keep readers on the edge of their seats. Can Dr. McCarthy save the lives of his patients infected with the deadly bacteria, who have otherwise lost all hope?
History

1997

1997

Author: Massimo Mastrogregori

Publisher: Walter de Gruyter

ISBN: 9783110950014

Category: History

Page: 415

View: 620

Annually published since 1930, the International bibliography of Historical Sciences (IBOHS) is an international bibliography of the most important historical monographs and periodical articles published throughout the world, which deal with history from the earliest to the most recent times. The works are arranged systematically according to period, region or historical discipline, and within this classification alphabetically. The bibliography contains a geographical index and indexes of persons and authors.
Medical

Foye's Principles of Medicinal Chemistry

Foye's Principles of Medicinal Chemistry

Author: Thomas L. Lemke

Publisher: Lippincott Williams & Wilkins

ISBN: 9781609133450

Category: Medical

Page: 1520

View: 201

Acclaimed by students and instructors alike, Foye's Principles of Medicinal Chemistry is now in its Seventh Edition, featuring updated chapters plus new material that meets the needs of today's medicinal chemistry courses. This latest edition offers an unparalleled presentation of drug discovery and pharmacodynamic agents, integrating principles of medicinal chemistry with pharmacology, pharmacokinetics, and clinical pharmacy. All the chapters have been written by an international team of respected researchers and academicians. Careful editing ensures thoroughness, a consistent style and format, and easy navigation throughout the text.
Political Science

Why the Left Hates America

Why the Left Hates America

Author: Daniel J. Flynn

Publisher: Crown Forum

ISBN: 9781400097470

Category: Political Science

Page: 288

View: 622

"The American flag stands for hatred, warmongering, and imperialism." "Our free-market system is responsible for killing and oppressing millions of people." "This country breeds racists and sexists." Is America really that bad? It is if you accept the lies and propaganda from the anti-American Left in our own country. This dismal, distorted view of the greatest, freest nation in history comes from a Left who would rather idolize Ho Chi Minh and Fidel Castro than honor George Washington and Thomas Jefferson, who burn down businesses and destroy property to protest free markets, and who fight alongside radical terrorists rather than against them. They trample the Constitution while hiding behind the First Amendment, and their idea of displaying the American flag is setting it on fire and parading it through the streets. Yes, this is a Left comprised of people who truly hate their country, and they will stop at nothing to tear her down—smashing our liberty in the process. Why the Left Hates America punches a hole right through the thin veneer of political correctness that has long protected these anti-Americans—exposing their rotting, vacuous core. Author and commentator Daniel J. Flynn digs deep into the American Left and reveals why they blame every bad deed in the world on the United States, while ignoring her myriad contributions. This book cogently points out that, of course, all Americans have the right to speak their minds. But, all too often, the actions by the anti-American Left become destructive and anarchistic. You need not look any further than the explosive 1999 World Trade Organization "protests" in Seattle, campus book burnings, or even John Walker Lindh to see that factions on the Left are the worst perpetrators of anti-Americanism. And what may be most shocking is that many of these anti-Americans are at the same time teachers, professors, journalists, news reporters, and even judges and politicians. Probing and controversial—without devolving into jingoism—this book proves once and for all that what you see in the news and learn in school is often tainted by the anti-American Left, and it shows you what you can do to keep them at bay.
Social Science

Defining Drugs

Defining Drugs

Author: Richard Henry Parrish II

Publisher: Routledge

ISBN: 9781351523141

Category: Social Science

Page: 163

View: 565

Drug-related morbidity and mortality is rampant in contemporary industrial society, despite or perhaps because, government has assumed a critical role in the process by which drugs are developed and approved. Parrish asserts that, as a people, Americans need to understand how it is that government became the arbiter of pharmaceutical fact. The consequences of our failure to understand, he argues, may threaten individual choice and forestall the development of responsible therapeutics. Moreover, if current standards and control continues unabated, the next therapeutic reformation might well make possible the sanctioned commercial exploitation of patients. In Defining Drugs, Parrish argues that the federal government became arbiter of pharmaceutical fact because the professions of pharmacy and medicine, as well as the pharmaceutical industry, could enforce these definitions and standards only through police powers reserved to government. Parrish begins his provocative study by examining the development of the social system for regulating drug therapy in the United States. He reviews the standards that were negotiated, and the tensions of the period between Progressivism and the New Deal that gave cultural context and historical meaning to drug use in American society. Parrish describes issues related to the development of narcotics policy through education and legislation facilitated by James Beal and Edward Kremers, and documents the federal government's evolving role as arbiter of market tensions between pharmaceutical producers, government officials, and private citizens in professional groups, illustrating the influence of government in writing enforceable standards for pharmaceutical therapies. He shows how the expansion of political rights for practitioners and producers has shifted responsibility for therapeutic consequences from individual practitioners and patients to government. This timely and controversial volume is written for the scholar and the compassionate practitioner alike, and a general public concerned with pharmacy regulation in a free society.
Science

Eurekas and Euphorias

Eurekas and Euphorias

Author: Walter Gratzer

Publisher: Oxford University Press on Demand

ISBN: 019860940X

Category: Science

Page: 357

View: 730

A collection of scientific anecdotes from the past two thousand years offers insight into the personalities, friendships, rivalries, deceptions, hoaxes, tragedies, and mistakes that marked the history of science. (Science & Mathematics)
Science

A Hidden Legacy

A Hidden Legacy

Author: Thomas E. Schindler

Publisher: Oxford University Press

ISBN: 9780197531693

Category: Science

Page:

View: 688

It's time to honor the significant scientific contributions of Esther Zimmer Lederberg. In A Hidden Legacy, Thomas E. Schindler shares the story of this remarkable microbiologist and offers insight into why her legacy has been obscured for so long. In the mid-20th century, microbiologist Esther Zimmer Lederberg and her then-husband, Joshua Lederberg, made a series of remarkable discoveries that contributed to the biochemical understanding of the gene. Together, they laid the foundation for molecular biology and the field of bacterial genetics. In 1958, he alone was awarded the Nobel Prize for their work. Esther's ingenuity was largely ignored and undervalued by the Nobel committee and has continued to be obscured by historians of science. In this book, Thomas E. Schindler shares many of Esther's hidden scientific contributions and her role in the discoveries that launched her then-husband's celebrated career. A Hidden Legacy delves into how, as a couple, the Lederbergs established a new field of bacterial genetics in the decade leading up to the discovery of the DNA double helix. Their impressive series of achievements includes the discovery of: *l bacteriophage and the first plasmid, known as the F-factor; how viruses carry bacterial genes between bacteria; and fundamental properties of bacterial sex. Schindler explains how Esther's research revealed unique features of bacterial sex that are now essential to our understanding of molecular biology and evolution. A magnificent story of a remarkable scientist, A Hidden Legacy takes readers through the process that scrambled the tree of life and offers insight into the role Esther played in uncovering these secretes of bacterial and viral genes.