Science

Transport Processes in Pharmaceutical Systems

Transport Processes in Pharmaceutical Systems

Author: Gordon L. Amidon

Publisher: CRC Press

ISBN: 9780824746322

Category: Science

Page: 746

View: 393

This cutting-edge reference clearly explains pharmaceutical transport phenomena, demonstrating applications ranging from drug or nutrient uptake into vesicle or cell suspensions, drug dissolution and absorption across biological membranes, whole body kinetics, and drug release from polymer reservoirs and matrices to heat and mass transport in freeze-drying and hygroscopicity. Focuses on practical applications of drug delivery from a physical and mechanistic perspective, highlighting biological systems. Written by more than 30 international authorities in the field, Transport Processes in Pharmaceutical Systems discusses the crucial relationship between the transport process and thermodynamic factors analyzes the dynamics of diffusion at liquid-liquid, liquid-solid, and liquid-cultured cell interfaces covers prodrug design for improving membrane transport addresses the effects of external stimuli in altering some natural and synthetic polymer matrices examines properties of hydrogels, including synthesis, swelling degree, swelling kinetics, permeability, biocompatibility, and biodegradability presents mass transfer of drugs and pharmacokinetics based on mass balance descriptions and more! Containing over 1000 references and more than 1100 equations, drawings, photographs, micrographs, and tables, Transport Processes in Pharmaceutical Systems is a must-read resource for research pharmacists, pharmaceutical scientists and chemists, chemical engineers, physical chemists, and upper-level undergraduate and graduate students in these disciplines.
Medical

Pharmaceutical Gene Delivery Systems

Pharmaceutical Gene Delivery Systems

Author: Alain Rolland

Publisher: CRC Press

ISBN: 9780203912331

Category: Medical

Page: 443

View: 889

This volume examines the advantages and limitations of the major gene delivery systems and offers guidelines to select the most appropriate viral or synthetic delivery system for specific therapeutic applications. It discusses advances in the design, optimization, and adaptation of gene delivery systems for the treatment of cancerous, cardiovascula
Medical

Pharmaceutical Process Scale-Up

Pharmaceutical Process Scale-Up

Author: Michael Levin

Publisher: CRC Press

ISBN: 9780824741969

Category: Medical

Page: 588

View: 248

Focusing on scientific and practical aspects of process scale-up, this resource details the theory and practice of transferring pharmaceutical processes from laboratory scale to the pilot plant and production scale. It covers parenteral and nonparenterel liquids and semi-solids, products derived from biotechnology, dry blending and powder handling,
Medical

Nanoparticulate Drug Delivery Systems

Nanoparticulate Drug Delivery Systems

Author: Deepak Thassu

Publisher: CRC Press

ISBN: 9781420008449

Category: Medical

Page: 376

View: 815

With the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. Nanoparticulate Drug Delivery Systems addresses the scientific methodologies, formulation, processing, applications, recent trends, and e
Medical

Transdermal Drug Delivery Systems

Transdermal Drug Delivery Systems

Author: Jonathan Hadgraft

Publisher: CRC Press

ISBN: 9780203909683

Category: Medical

Page: 328

View: 650

Presents authoritative state-of-the-art discussions of the key issues pertinent to transdermal drug delivery, examining those topics necessary to enable a critical evaluation of a drug candidate's potential to be delivered across the skin; from physical chemistry and assessment of drug permeability to available enhancement technolgies, to regulator
Medical

Introduction to the Pharmaceutical Sciences

Introduction to the Pharmaceutical Sciences

Author: Nita K. Pandit

Publisher: Lippincott Williams & Wilkins

ISBN: 9780781744782

Category: Medical

Page: 419

View: 805

This unique textbook provides an introductory, yet comprehensive overview of the pharmaceutical sciences. It is the first text of its kind to pursue an interdisciplinary approach in this area of study. Readers are introduced to basic concepts related to the specific disciplines in the pharmaceutical sciences, including pharmacology, pharmaceutics, pharmacokinetics, and medicinal chemistry. In an easy-to-read writing style, the book provides readers with up-to-date information on pharmacogenomics and includes comprehensive coverage of industrial drug development and regulatory approval processes. Each chapter includes chapter outlines and critical-thinking exercises, as well as numerous tables and graphs. More than 160 illustrations complement the text.
Science

Transport Phenomena in Biological Systems

Transport Phenomena in Biological Systems

Author: George A. Truskey

Publisher: Prentice Hall

ISBN: 0130422045

Category: Science

Page: 793

View: 239

A textbook for graduate or advanced undergraduate students who have had some exposure to biology though the fundamentals are reviewed but no previous experience with mass and momentum transport or chemical kinetics. It integrates biological and engineering concepts to develop transport equations, an
Medical

Pharmaceutical Inhalation Aerosol Technology, Second Edition

Pharmaceutical Inhalation Aerosol Technology, Second Edition

Author: Anthony J. Hickey

Publisher: CRC Press

ISBN: 9780824756642

Category: Medical

Page: 628

View: 703

This thoroughly revised and expanded reference provides authoritative discussions on the physiologic, pharmacologic, metabolic, molecular, cellular and physicochemical factors, influencing the efficacy and utilization of pharmaceutical aerosol. It analyzes the latest science and developments in the generation, administration and characterization of these compounds, showcasing current clinical applications, the efficiency and limitations of major aerosol products and emerging aerosol therapies impacting the field.
Medical

Pharmaceutical Photostability and Stabilization Technology

Pharmaceutical Photostability and Stabilization Technology

Author: Joseph T. Piechocki

Publisher: CRC Press

ISBN: 9781420014136

Category: Medical

Page: 445

View: 565

Based on a training course developed by Dr. Joseph T. Piechocki and other experts in this field whose contributions appear in this book for two International Meetings on the Photostability of Drugs and Drug Products, this text clarifies the guidelines set by the International Conference on Harmonization (ICH) and provides a comprehensive background
Medical

Freeze-Drying/Lyophilization Of Pharmaceutical & Biological Products, Revised and Expanded

Freeze-Drying/Lyophilization Of Pharmaceutical & Biological Products, Revised and Expanded

Author: Louis Rey

Publisher: CRC Press

ISBN: 9780203021323

Category: Medical

Page: 634

View: 130

Thoroughly acquainting the reader with freeze-drying fundamentals, Freeze-Drying/Lyophilization of Pharmaceutical and Biological Products, Second Edition carves practical guidelines from the very latest theoretical research, technologies, and industrial procedures. It delineates the best execution of steps from closure preparation and regulatory control of products to equipment sterilization and process validation. With 13 new chapters providing state-of-the-art information, the book unveils innovations currently advancing the field, including LYOGUARD® packaging for bulk freeze-drying and the irradiation of pharmaceutical and biological products.
Medical

Good Manufacturing Practices for Pharmaceuticals

Good Manufacturing Practices for Pharmaceuticals

Author: Joseph D. Nally

Publisher: CRC Press

ISBN: 9781420020939

Category: Medical

Page: 424

View: 421

With global harmonization of regulatory requirements and quality standards and national and global business consolidations ongoing at a fast pace, pharmaceutical manufacturers, suppliers, contractors, and distributors are impacted by continual change. Offering a wide assortment of policy and guidance document references and interpretations, this Sixth Edition is significantly expanded to reflect the increase of information and changing practices in CGMP regulation and pharmaceutical manufacturing and control practices worldwide. An essential companion for every pharmaceutical professional, this guide is updated and expanded by a team of industry experts, each member with extensive experience in industry or academic settings.
Medical

Handbook of Pharmaceutical Controlled Release Technology

Handbook of Pharmaceutical Controlled Release Technology

Author: Donald L. Wise

Publisher: CRC Press

ISBN: 9781482289985

Category: Medical

Page: 902

View: 312

The Handbook of Pharmaceutical Controlled Release Technology reviews the design, fabrication, methodology, administration, and classifications of various drug delivery systems, including matrices, and membrane controlled reservoir, bioerodible, and pendant chain systems. Contains cutting-edge research on the controlled delivery of biomolecules!